Motoring ahead with rodents

Citation:

Ölveczky BP. Motoring ahead with rodents. Curr Opin Neurobiol. 2011;21 :571-8.

Date Published:

Aug

Abstract:

How neural circuits underlie the acquisition and control of learned motor behaviors has traditionally been explored in monkeys and, more recently, songbirds. The development of genetic tools for functional circuit analysis in rodents, the availability of transgenic animals with well characterized phenotypes, and the relative ease with which rats and mice can be trained to perform various motor tasks, make rodents attractive models for exploring the neural circuit mechanisms underlying the acquisition and production of learned motor skills. Here we discuss the advantages and drawbacks of this approach, review recent trends and results, and outline possible strategies for wider adoption of rodents as a model system for complex motor learning.

 Aug 2011 (pdf)

Notes:

Olveczky, Bence PengR01 NS66408/NS/NINDS NIH HHS/Research Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tEngland2011/06/02 06:00Curr Opin Neurobiol. 2011 Aug;21(4):571-8. doi: 10.1016/j.conb.2011.05.002. Epub 2011 May 31.

Last updated on 11/30/2015